GENE AMPLIFICATIONS
REMBRANDT® EGFR amplification detection
Technology | FISH | ISH |
| Application | Gene amplification | Gene amplification |
| Area of interest | Formalin-fixed paraffin-embedded tissue section or fixed cytological specimen | Formalin-fixed paraffin-embedded tissue section or fixed cytological specimen |
| Region | 7p11.1-q11.1 and 7p11.2 | 7p11.1-q11.1 and 7p11.2 |
| Label | ♦ (AF488, 2000) and ♦(AF555, 3000) | Biotin (0100) and Digoxigenin (9900) |
| Product No. | C816K.2030.05 | C816K.0199.05 |
| C816K.2030.10 | C816K.0199.10 | |
| Product Type | In vitro diagnostics (IVD) or Research use only (RUO) | Research use only (RUO) |
| Intended Use | The REMBRANDT® EGFR amplification FISH detection assay is designed to target the EGFR gene (7p11.2) compared to a CEP7 control probe which allows to detect amplifications of EGFR and simultaneous enumeration of chromosome 7. | The REMBRANDT® EGFR amplification ISH detection assay is designed to target the EGFR gene (7p11.2) compared to a CEP7 control probe which allows to detect amplification of EGFR and simultaneous enumeration of chromosome 7. |
| Kit contents | C816P.2030 LSI 7p11.2/CEP7 FISH probe mix | C816P.0199 LSI 7p11.2/CEP7 ISH probe mix |
| R018R.0000 Pepsin diluent | R018R.0000 Pepsin diluent | |
| R011R.0000 Pepsin powder | R011R.0000 Pepsin powder | |
| R025R.0000 PanWash 4, 25x SSC | R025R.0000 PanWash 4, 25x SSC | |
| R026R.0000 Pre-treatment buffer | R026R.0000 Pre-treatment buffer | |
| Z000R.0050 Fluorescent mounting medium |
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All products are also available as stand-alone RUO products